25 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... ulcerations • Skin ... ulcerations • Auricular skin ... • Skin vasculopathies
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Infection #clinical #photo
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Disorders #Algorithm #Differential
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Capnocytophaga Canimorsus Skin ... colonize human skin ... dogs & latter can cause ... Capnocytophaga #Canimorsus #Skin ... #clinical #photo
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... Polyneuropathy, Cranial nerve ... erythematosus #signs ... #symptoms #diagnosis
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... processes occur in the skin ... -> Heliotrope Rash ... Pathophysiology #Signs ... #Symptoms #Vasculitis
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... Skin rash and malaise ... The signs and symptoms ... resembling rashes caused ... Diagnosis #Clinical #Photo
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... rash in association ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Malar (butterfly) Rash ... pathophysiology #diagnosis #signs ... #symptoms #complications