21 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #pain #skin #rashes ... #differential #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... erythematosus #signs ... #symptoms #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... - Skin, glomeruli ... glomerular ischemia - Skin ... Small Vessels: Skin
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
- Differential Diagnosis ... arthritis - with the skin ... Erythematosus (SLE ... should have other symptoms ... like “butterfly rash
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... Skin lesions ... also occur Skin ... 16%) • Painful skin ... and gangrene Skin
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Fever, malaise • Rash ... testing • No symptoms ... lesions in bone, skin ... unknown - VA Joint ... #signs #diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... : • Skin lesions
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... inflammation on skin ... Livedo Reticularis, Vasculitis ... pathophysiology #diagnosis #signs ... #symptoms #complications
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Purpura (HSP, IgA Vasculitis ... abdominal pain, joint ... #clinical #photo ... #dermatology #skin ... #rash #physicalexam