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diagnosis differential dermatology endocrinology pain rheumatology vasculitis 21hydroxylasedeficiency 21ohd abdominal acromegaly algorithm arterial biliary cauda caudaequina cholangitis chronic cirrhosis classification
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... Causes: 1) Exfoliative ... Basophils/Histamine 4) Skin-homing ... Nikolsky #Algorithm #Differential
Diabetic Foot: Pathogenesis and clinical findings • Polyol Pathway - Excess glucose enters Polyol pathway ->
Glycosylation - AGE cause ... - Breakdown of skin ... , resulting in skin ... #DiabeticFoot #pathophysiology ... #complications
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Pathogenesis and Complications ... RBCs, WBCs, and skin ... Release of purine bases ... Hyperuricemia #Pathophysiology ... #Complications
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... Manifestations #pathophysiology ... signs #symptoms #complications
Pulse Oximetry Summary Pulse oximetry is the non-invasive continuous measurement of the oxygen saturation of hemoglobin. It
deoxy hemoglobin differentially ... Shine Red and IR ... light through the skin ... such as after a pause ... #critcalcare #pathophysiology
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... gyratum repens • A skin ... induratum • A chronic skin ... PrathitKulkarni #Erythemas #comparison ... #table #differential
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Heat Stroke - Differential ... blisters on the skin ... Collapse: • Pathophysiology ... Pale and sweaty skin ... #diagnosis #causes
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