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differential dermatology hematology vasculitis algorithm syndrome pain alopecia causes clinical hairloss joint lupus skin sle systemic blood classification cryoglobulinemia dermatomyositis
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... Skin Biopsy
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Diagnosis Framework ... thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... skin • Inflammation
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... Nikolsky sign, the differential ... Kawasaki disease ... Febrile #Fever #Differential
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... signs #symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Small Vessels: Skin ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... #Diagnosis #Rheumatology
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
wax and wane; diagnosis ... trauma leads to skin ... Papulonodular, erythematous ... biopsy preferred Differential ... Infection #clinical #photo
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