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differential syndrome erythematosus sle systemic dermatology hematology joint oncology pain signs stills vasculitis abdominal adult adultonset algorithm aosd arthropathies arthropathy
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... arthritis - with the skin ... with Systemic Lupus ... should have other symptoms
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Small Vessels: Skin ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Seizures • Strokes Skin ... : • Symptoms limited ... #Rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... ) Differential Diagnosis ... #symptoms #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Symptoms: • The ... Skin involvement ... Resolution > 15 days Differentials ... #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... • Affects the skin ... cmpkx deposits skin ... Vasculitis: • Skin ... #Diagnosis #Rheumatology
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