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differential dermatology erythematosus systemic vasculitis classification joint signs skin symptoms syndrome algorithm ana antibodies antinuclear behcet blanching causes clinical conditions
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(15%) Skin (85% ... Polyneuropathy, Cranial nerve ... lesions Abdominal pain ... signs #symptoms #diagnosis ... #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #skin #rashes # ... differential #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Associated with skin ... heart block • Sjogren ... #Summary #diagnosis ... #rheumatology # ... management
Scleroderma Associated Telangiectasia. If you see them-round, often well circumscribed (but can be matte-like too) &
& blanchable, differential ... especially SSc, SLE ... , Sjogrens, MCTD ... #blanching #skin ... #dermatology #rheumatology
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 Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... erythematosus (SLE ... ), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... dermatomyositis, Sjogren ... Arthritis: • Joint pain ... Seizures • Strokes Skin
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Small Vessels: Skin ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... enlargement - Sjögren's ... Scleroderma Thickened skin ... #differential # ... diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... , Sjogren's ... #Diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... reticularis & skin ... Labs/Diagnosis: ... (e.g. systemic lupus ... classification #rheumatology
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