33 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Diagnosis Framework ... thrombophlebitis Skin ... • Shin splints ... Brittle nails - Skin ... skin • Inflammation
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Diagnosis Algorithm ... Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Myelodisplastic syndrome
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... signs #symptoms #diagnosis
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... Diagnosis Algorithm ... arthritis - (Reiter’s syndrome ... arthritis - with the skin ... #Diagnosis #Algorithm
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #SLE #Summary #diagnosis ... #rheumatology #management
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
and C viruses. systemic ... and Sjogren's syndrome ... in absence of skin ... Vasculitides #vasculitis #differential ... #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Purpura, ischemic skin ... - Affects the skin ... glomerular ischemia - Skin ... Diagnosis: Systemic ... Small Vessels: Skin
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Eosinophilia - Differential ... Diagnosis Algorithm ... GI, lung, skin), ... B-cell lymphomas), Systemic ... #Diagnosis #Algorithm
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
wax and wane; diagnosis ... trauma leads to skin ... , painless, no systemic ... biopsy preferred Differential ... Infection #clinical #photo
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... characterized by extensive skin ... Skin involvement ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome