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diagnosis dermatology differential management symptoms causes dermatomyositis disease erythematosus lupus sle syndrome systemic vasculitis adultonset algorithm antimda5 antimda5dm antinxp2 antinxp2dm
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #skin #rashes # ... #rheumatology
Leser–Trélat Sign on Physical Exam Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy. #Leser
Leser–Trélat Sign ... paraneoplastic sign ... #PhysicalExam #clinical ... #video #skin #dermatology ... #oncology
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 Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... lesions Abdominal pain ... erythematosus #signs
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... and gangrene Skin
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Syndrome) is a skin ... inflamed or blistered skin ... development of skin ... deeper into the skin ... small samples of skin
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Ill-appearing, vital sign ... sulfa-drug - Skin ... pain - Immunocompromised ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Lymphocutaneous Sporotrichiosis Infection Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis? Lymphocutaneous
painless nodular rash ... trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... Sporotrichiosis #Infection #clinical
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... fraction < 20% Differential ... management #treatment #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
ulcerations • Skin ... ulcerations • Auricular skin ... auricular papules Clinical ... 50% of cases • Skin ... Dermatomyositis #rheumatology
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