45 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
lupus erythematosus ... , Drug-induced Lupus ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Associated with skin ... block • Sjogren syndrome ... #Lupus #Erythematosus ... Summary #diagnosis #rheumatology
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... • Bullous systemic ... lupus erythematous ... Vesiculobullous #SkinRash ... #dermatology #Differential
Genital Skin Ulcers - Differential Diagnosis Algorithm
Painful:
 • Herpes simplex
 • Haemophilus ducreyi (chancroid)
 • Behcet's
Genital Skin Ulcers ... - Differential ... ) • Behcet's syndrome ... Ulcers #ulcerative #skinrash ... #dermatology #Differential
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Wiskott-Aldrich syndrome ... Autoimmune Diseases: • Systemic ... lupus erythematosus ... #Diagnosis #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Causes == Primary Skin ... • Xerosis (dry skin ... == No Primary Skin ... Myelodisplastic syndrome ... #generalized #dermatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... lupus. ... CTILD #Diagnosis #Differential ... Table #Pulmonary #Rheumatology
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
Combination of Skin ... on texture of skin ... Suggestive of systemic ... #arthritis #skin ... #differential #