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diagnosis differential dermatology algorithm management vasculitis syndrome causes hematology joint lupus pain signs sle symptoms classification msk oncology sclerosis treatment
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
anti-Sc170): Diffuse skin ... Anti-centromere: Limited skin ... hypertension, Digital ulcers ... Rapid progressive skin ... Autoantibodies #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
progressive fibrosis of skin ... LcSSc) - distal skin ... DcSSc; diffuse) - skin ... changes): skin ... Raynaud's, digital ulcers
Oral Skin Ulcers - Differential Diagnosis Algorithm Single Ulcer: • Traumatic ulcer • Angular ulcer • Aphthous
Oral Skin Ulcers ... - Differential ... planus • Lupus erythematosus ... #Oral #mouth #SkinRash ... #dermatology #Differential
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Skin Conditions ... Scleroderma Thickened skin ... arthritis Discoid skin ... #joint #pain #skin ... #rashes #differential
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
thrombophlebitis Skin ... band syndrome • Shin ... Brittle nails - Skin ... ulcers - Shiny ... skin • Inflammation
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis Malar rash: • A
Combination of Skin ... on texture of skin ... Suggestive of systemic ... • Small penile ulcers ... dermatology #arthritis #skin
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Polyneuropathy, Cranial nerve ... pain (20%) Renal disease ... #erythematosus ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Associated with skin ... • MCTD (SLE/systemic ... #Lupus #Erythematosus ... Summary #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... - Affects the skin ... Cryoglobulinemic Vasculitis - Skin ... glomerular ischemia - Skin ... Small Vessels: Skin
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... vasculitis Skin ... also occur Skin ... 16%) • Painful skin ... Skin Biopsy
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