82 results
Generalized Hyperpigmentation Differentials
Use the Mnemonic "no skin SPARED"

Images from dermnet.nz and merckmanuals

Mnemonic from https://www.medscape.com/slideshow/dermatology-mnemonics-6011359#5 #diagnosis #differential
the Mnemonic "no skin ... dermatology-mnemonics-6011359#5 #diagnosis ... #differential # ... symptoms #signs ... #dermatology #skin
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... DcSSc; diffuse) - skin ... changes): skin ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... neuropathies • Skin ... dysrhythmias • Ophthalmologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... or symptoms (eg ... , skin or esophageal ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Infective Endocarditis

General 
 - Malaise 
 - Clubbing 

Cardiac 
 - Murmurs
Clinical Features ... Pyrexia Skin ... #Endocarditis #Symptoms ... #Signs #Features ... #PhysicalExam #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #management #signs ... #symptoms #rheumatology
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... intestines, extremities Skin ... (Skin and Mucosa ... #anaphylaxis #signs ... #symptoms #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
life Causes and clinical ... trigger - Direct skin ... 50% of patients Skin ... 1% of patients Skin ... #rheumatology #
CREST Syndrome: Pathogenesis and Clinical Findings

CALCINOSIS (BB-sized, hard nodules in fingers)
RAYNAUD'S Phenomenon
ESOPHAGEAL DYSMOTILITY
SCLERODACTYLY (thickening and tightening
Pathogenesis and Clinical ... tightening of skin ... Pathophysiology #Diagnosis ... #Signs #Symptoms