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diagnosis management rheumatology differential causes erythematosus lupus sle activation cell cerebritis cns criticalcare cryoglobulinemia cryoglobulins disease disorders hemeonc hemophagocytic histiocytosis
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... dysfunction ... multifactorial mechanisms Hematologic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... Syndrome: • Clinical ... #classification ... #rheumatology #
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
IL-1 and IL-6, leading ... fever syndromes Clinical ... Fever is the main clinical ... (CNS) dysfunction ... Diagnosis #Management #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE) Clinical ... Encephalopathy, Cognitive Dysfunction ... inflammation, leading ... CNS #neurology #rheumatology
Causes, classification and compensatory responses to shock. Shock can be caused by any pathological process that leads
Causes, classification ... vasodilatation, myocardial dysfunction ... shock is often clinically ... renin–angiotensin–aldosterone system ... Differential #Causes #Types
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... Qualitative defect (i.e. dysfunctional ... Bleeding: Severe (Clinically ... VonWillebrand #Disease #Classification ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Malignancy (e.g. hematologic ... Kikuchi disease • Type-I ... mild cognitive dysfunction
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... specific) COMMON CLINICAL ... • Pancreas: Type ... complement • Classification
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
virtually any organ system ... Langerhans cells, a type ... various tissues, leading ... populations) CLINICAL ... Single-System (Low
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