20 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Dermatomyositis ... can present with rash ... , Shaw sign, holster ... sign, and Gottron's ... Myositis #diagnosis #rheumatology
Reversed Halo Sign - Infectious and Non-Infectious Differential Diagnosis
Definition: A focal rounded area of GGO surrounded
Reversed Halo Sign ... Non-Infectious Differential ... • Infectious Causes ... , Sarcoidosis, Dermatomyositis ... Reverse #Halo #Sign
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
(blue-purple) rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... #rheumatology #
Shawl sign poikiloderma in Dermatomyositis

Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... along with other signs ... symptoms helps differentiate ... RashDecisionz #Shawl #sign ... #Rash #Dermatomyositis
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
with heliotrope rash ... , shawl sign, and ... out this is a case ... , 2) shawl sign, ... skinrash #shawl #sign
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies Dermatomyositis ... heliotrope, shawl sign ... Inflammatory #Myopathies #differential ... diagnosis #comparison #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
69% - Malar rash ... (aPL) 30-45% Differential ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin Rash ... - Differential ... Auspitz sign, Koebner's ... #Differential # ... Diagnosis #Algorithm #causes
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... chest (in a V-sign ... shoulders (in a shawl sign ... Muscle atrophy may cause ... diagnosis #management #rheumatology