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antibiotics fever hematology infant lp stepbystep stratification alcohol apml aws differentiation disease ebm encephalopathy etoh features hemophagocytic hlh kawasaki leukostasis
Validation of the Step-By-Step Approach to Febrile Infants #Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Infants #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... Infant #StepByStep #Algorithm ... #Antibiotics #Risk
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
systemic acute febrile ... immunoglobulin reduces the risk ... Disease #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... components of the algorithm ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
The Febrile Infant ... empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... : - If febrile ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Attempt if high risk ... Rare: DAH, acute febrile ... : >3 symptoms, or ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... acute or subacute febrile ... #management #treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... Risk factors 3. ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
Alcohol Withdrawal Syndrome (AWS) - ICU OnePager Scoring Alcohol Withdrawal Syndrome (AWS): • PAWSS • CIWA-Ar •
Withdrawal Symptom ... 3% - High risk ... with normal vital signs ... #AWS #diagnosis ... #treatment #management
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