11 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... erythematosus #signs ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... < 30 years - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Marantic Endocarditis 

Epidemiology:
 - Incidence of non-bacterial thrombotic endocarditis (marantic endocarditis if associated with cancer) is
patients with no signs ... /syrnptoms of embolic ... Clinical Findings ... on mitral and aortic ... Diagnosis #Management #Cardiology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... < 30 years • Aorta ... Arteritis): • Aorta ... Diagnosis #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... Behcet syndrome (Clinical ... Behcet disease) Differential ... diagnosis #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Diagnosis = clinical ... systemic sx + signs ... required due to skip ... GCA #Temporal #Signs
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Pathogenesis and clinical ... ) - Ischemic Skin ... Takayasus #Arteritis #Vasculitis ... #Diagnosis #Signs ... #Symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... permanent alopecia Differential ... Induced Lupus: • Symptoms ... • Cervical cancer
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... Hepatomegaly • Skin
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... and/or symptoms ... - Sjogren - Vasculitis ... management #neurology #differential