32 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... Crises can be precipitated ... The underlying pathophysiology ... 4 different mechanism ... of the baseline anaemia
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes ... #Pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
• chronic anæmia ... - Sickle cell anemia ... Dissociation #Curve #Pathophysiology ... #Differential #Causes
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
Alexia Without Agraphia ... Alexia without ... the most common cause ... is being read (alexia ... MoiseyWoisey #Alexia
Benzodiazepines: Mechanism of Action and Side Effects
 • Decr spinal cord activity -> Muscle relaxant
Benzodiazepines: Mechanism ... - Anterograde amnesia ... confusion - Ataxia ... #Pharmacology #pathophysiology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... pancytopenia Mechanisms ... Immune Aplastic Anemia ... and petechiae Causes
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Mood Stabilizers: Mechanism ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... MoodStabilizers #Mechanism ... #SideEffects #Pathophysiology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... Metabolism Severe Anemia ... HeartFailure #CHF #Pathophysiology ... Diagnosis #cardiology #causes
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... is rare (< 10% cases ... ), cough (30% cases ... immature forms) • Anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... l MD SOAP) - Risks ... practices that could cause ... changes), high MCV anemia ... patients if the cause