16 results
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose: Mechanism ... Lactulose → ↑ Lactic Acid ... , Acetic Acid → ... #ammonia #hepatology ... #pathophysiology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: ... Mechanism of Action ... analog of the amino acid ... #pathophysiology ... #hematology #TXA
Pathways Involved in Protein and Amino Acid Metabolism in Chronic Kidney Disease. The tricarboxylic acid (TCA)
Protein and Amino Acid ... tricarboxylic acid ... metabolize amino acids ... These mechanisms ... #Pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Mechanism of Action ... Bile Acid Sequestrants ... ↓ Hepatic Bile Acid ... ↑ Hepatic Bile Acid ... sequestration #pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Pharmacology #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Mechanisms Driving ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... fetal free fatty acid ... Intermediate fatty acid ... Liver #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Mechanism of Gastric HCL secretion and production

#gastric #acid #secretion #pathophysiology
Mechanism of Gastric ... production #gastric #acid ... #secretion #pathophysiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
stimulated by bile acid ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology