21 results
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Mechanisms Driving ... Thrombosis and Bleeding ... #Thrombosis #Bleeding ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... first variceal bleeding ... Prevention of variceal rebleeding ... BetaBlockers #Cirrhosis #hepatology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose: Mechanism ... #pharmacology #mechanism ... #ammonia #hepatology ... #pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Pharmacology #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Inflammatory, Immunologic, and Pathobiologic Features Leading to Severe Asthma. #Pathophysiology #Asthma #Mechanism #Leukotriene #Type2 #Inflammatory #Immunologic
Pathobiologic Features Leading ... #Pathophysiology ... #Asthma #Mechanism
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: Mechanism ... Tranexamic #Acid #pathophysiology ... #hematology #TXA
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Cell Disease - Pathophysiology ... membrane damage leading ... the vital organs leading ... SickleCell #Disease #Pathophysiology ... Complications #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... protein C and S Pathophysiology ... Findings: • Bleeding ... transfusion for bleeding ... treatment #management #hematology
Pathophysiology of Hepatorenal Syndrome - Dilation of splanchnic arteries initially compensated by increased CO eventually decompensates
Pathophysiology ... activation of mechanisms ... RAAS, SNS, ADH) leading
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology