15 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... AntiCoagulation #Cascade ... #Pharmacology #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Phagocytosis: (main mechanism ... #Inflammatory #Cascade ... #Inflammation #pathophysiology
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
#Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose: Mechanism ... #pharmacology #mechanism ... #ammonia #hepatology ... #pathophysiology
Non-Infective Endocarditis - Pathophysiology
Non-infective Endocarditis Pathophysiology:
 • Valves usually undamaged - Etiology poorly understood but thought
Endocarditis - Pathophysiology ... Non-infective Endocarditis Pathophysiology ... different interacting mechanisms ... activation of clotting cascade ... NBTE #Marantic #pathophysiology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Biliary Cirrhosis - Pathophysiology ... relative with PBC Pathophysiology ... mediated autoimmune cascade ... Biliary #Cirrhosis #Pathophysiology ... #hepatology
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: Mechanism ... Tranexamic #Acid #pathophysiology ... #hematology #TXA
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Mechanisms Driving ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... #Coagulation #Cascade ... diagnosis #models #hematology ... #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
occur via numerous mechanisms ... the complement cascade ... #Pharmacology #Pathophysiology