9 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Pharmacology #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
Lactulose: Mechanism ... #pharmacology #mechanism ... #ammonia #hepatology ... #pathophysiology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Fondaparinux #NOAC ... #Mechanism
Tranexamic Acid: Mechanism of Action
 - TXA is an anti-fibrinolytic
 - TXA is a synthetic analog
Tranexamic Acid: Mechanism ... Tranexamic #Acid #pathophysiology ... #hematology #TXA
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Mechanisms Driving ... Clot #Cirrhosis #Pathophysiology ... #Hepatology #Liver
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 2 hit mechanism ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... , Bivalirudin, DOAC ... Management #Treatment #Hematology
Inherited forms of Hyperbilirubinemia
Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
The mechanism responsible ... Hyperbilirubinemia #pathophysiology ... #congenital #hepatology
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... be behind the mechanism ... cirrhosis #diagnosis #hepatology