17 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
(blood). ... features in most cases ... #APL #APML #Pathology ... #Hematology #Clinical ... #Smear
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
hospitalization and treatment ... her peripheral blood ... smear showed hypogranular ... Clinical #Path #BloodSmear ... #Blood #Smear #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... smear or on bone ... : Blast crises ... • Peripheral smear ... #Hematology #Oncology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... not required in all ... dysplasia on the smear ... #Workup #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Peripheral smear ... Lymphocytosis: Absolute blood ... microglobulin Treatment ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... smear • Bone marrow ... Syndromes #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... ABO incompatible blood ... protein C and S Pathophysiology ... • Peripheral smear ... #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Puncture, EEG Treatment ... (for secondary APS