163 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... plateletcount), peripheral blood ... smear, HIV/HCV ... dysplasia on the smear ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
type ± C3d • Blood ... smear: Differential ... 2) LOOK FOR a cause ... #management #treatment ... #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Normochromic RBCs on Smear ... #Algorithm #Causes ... #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... features in most cases ... APML #Pathology #Hematology ... #Clinical #Smear
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... and Management ... Reticulocytes, smear ... MAHA likely: • Smear ... #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... arrow) Peripheral smear ... hemolytic #anemia #Hematology ... #Pathology #Smear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Peripheral Smear ... → Refer to hematology ... : Acute blood loss ... #Differential #Diagnosis
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Algorithm Normal Blood ... Smear • Drugs ... #Hematology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
urinalysis, labs - Management ... Glomerular (red blood ... eosinophils/white blood ... renal biopsy - Management ... ultrasonography - Manaqement
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
- Differential Diagnosis ... Reactive: • Anemia/blood ... #Differential #Diagnosis ... #causes #Platelets ... #hematology