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diagnosis algorithm hypercalcemia growthhormone hyperthyroidism management pituitary treatment workup acromegaly feedbackloop glftap highthyroid hirsutism hypertension hypocalcemia indications iodine macroadenoma masseffects
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... GH excess prior ... GH excess after ... • Other rare causes ... signs #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... excess: - ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
causes 3) Assess ... for non-hormonal ... causes by Lauren ... Diagnosis #algorithm #endocrinology ... #calcium
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
For pituitary masses ... following order; GH ... Headaches • Nausea ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake Reduced uptake: • Thyroiditis • Exogenous
Differentiation of Causes ... Ectopic thyroid hormone ... Graves' disease • Excess ... radionuclide #uptake #differential ... hyperthyroidism #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
excess occurs before ... islet cell tumor, excess ... Differential Diagnosis ... or refractory cases ... Diagnosis #Management #Endocrinology
Hypercalcemia - Differential Diagnosis Algorithm Elevated PTH (High or normal): • Primary Hyperparathyroidism • Familial Hypocalciuric Hypercalcemia Low
Hypercalcemia - Differential ... Cholecalciferol - Excess ... Bony Mets - Calcium ... Diagnosis #Algorithm #causes ... #endocrinology
Hyperthyroidism - Differential Diagnosis Algorithm High/Normal Radioiodine Uptake - Autoimmune Thyroid Disease: • Grave's
Hyperthyroidism - Differential ... Goiter - TSH/HCG Excess ... Exogenous/Ectopic Hormone ... Diagnosis #Algorithm #endocrinology ... #causes
Hirsutism & Virilization - Differential Diagnosis Algorithm ADRENAL EXCESS Ovarian • Polycystic Ovarian Syndrome • Hyperthecosis • Tumor Adrenal
Virilization - Differential ... Algorithm ADRENAL EXCESS ... Tumor Low Serum Hormone ... Diagnosis #Algorithm #endocrinology ... #causes
Causes of Hypercalcemia Parathyroid hormone–dependent Primary hyperparathyroidism Familial hypocalciuric hypercalcemia Lithium-associated Tertiary hyperparathyroidism Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... humoral syndromes Excess ... Hypercalcemia #Causes ... #Differential # ... Diagnosis #Endocrinology
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