23 results
Elliptocyte - 
Note the shape of these appropriately named erythrocytes.
In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... sideroblastic anemia ... #Clinical #Path ... BloodSmear #Blood #Smear
Dacrocytes (tear drop cells) 
Other poikilocytes resemble a pear or teardrop. The narrow, tapered end
may be
metaplasia, pernicious anemia ... some hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Peripheral blood smear ... Malaria, Clostridium ... Differential #Diagnosis #Algorithm
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
peripheral blood smear ... iron deficiency anemia ... #Clinical #Path ... PeripheralBloodSmear #BloodSmear #Anemia
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Differential Diagnosis Algorithm ... Signs of anemia ... Abnormal peripheral smear ... Differential #Diagnosis #Algorithm
Plasmodium - Identification Algorithm
 • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Identification Algorithm ... gametocytes • P. malariae ... Identification #Algorithm ... #pathology #smear ... #microscopy #malaria
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Differential Diagnosis Algorithm ... Normochromic RBCs on Smear ... Spherocytes on Smear ... Differential #Diagnosis #Algorithm
Codocytes (Target cells) - Two target cells are seen in the left photo and one in
with hemolytic anemias ... #Clinical #Path ... BloodSmear #Blood #Smear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Infections/toxins: Malaria ... Defects: Sickle cell anemia ... Peripheral Blood Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Normal Blood Smear ... • Pernicious Anemia ... Differential #Diagnosis #Algorithm