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management nephrology medications syndrome agitation aki causes clozapine colchicine coronavirus covid19 criticalcare delirium differential diuresis diuretics druglevels encephalopathy excretion icu
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2 Chloroquine and Hydroxychloroquine • Mechanisms: Interference with ligand
: Drug-drug interactions ... neuropathy, lactic acidosis ... , renal injury ( ... medications), hypotension ... #Toxicology #Medications
Propofol-Related Infusion Syndrome (PRIS) Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Syndrome (PRIS) Diagnosis ... • Metabolic acidosis ... Hyperkalemia and renal ... #Management #Pharmacology ... #Toxicity #Toxicology
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
antipsychotic drugs ... with a mix of renal ... of orthostatic hypotension ... #Toxicity #Diagnosis ... #Pharmacology
Vancomycin Associated Acute Kidney Injury • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... particularly underlying renal ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis ... #management #nephrology
Phases of Colchicine Toxicity - Early Phase (0-24h) - Multi-organ failure Phase (1-7 days)
cardiac arrest Neurologic ... hyperglycemia Other: Renal ... #Toxicology #Phases ... #Pharmacology # ... Diagnosis
Therapeutic Drug Level Monitoring Carbamazepine - Sample immediately before next dose (trough) Clozapine - Sample immediately
Therapeutic Drug ... at anytime if toxicity ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Immunosuppressive agents, Renal ... abnormality, Medication/Drug ... toxicity, Metabolic ... #management #neurology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... Excretion #Diuresis #Nephrology ... #Pharmacology # ... Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Toxins - Drugs ... injured muscles - HYPOTENSION ... per day until stable ... #Differential #Diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU Addressing the ICU Triad (PAD) can be accomplished through
, bradycardia. renal ... A dissociative drug ... glycol (solvent) toxicity ... No pharmacologic ... #CriticalCare #diagnosis
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