11 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
Know" series - Drug ... vary depending on treatment ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Kidney Injury • Drug ... particularly underlying renal ... • Treatment includes ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... antipsychotic drugs ... with a mix of renal ... #Toxicity #Diagnosis ... #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
- Differential Diagnosis ... Drugs (Statins), ... injured muscles -> HYPOTENSION ... per day until stable ... #Differential #Diagnosis
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... disequilibrium syndrome • Diagnosis ... Tolvaptan) • Treatment ... #Pharmacology # ... Medications #Table
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Immunosuppressive agents, Renal ... abnormality, Medication/Drug ... epilepticus Treatment ... #management #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... - Toxins - Drugs ... injured muscles - HYPOTENSION ... per day until stable ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Excretion: - Renal ... 15 suggests ↓ renal ... Elimination (see Table ... #potassium #nephrology
Reported Mechanisms and Toxicity of Investigational Treatments for SARS-COV-2
Chloroquine and Hydroxychloroquine
 • Mechanisms: Interference with ligand
Investigational Treatments ... neuropathy, lactic acidosis ... , renal injury ( ... medications), hypotension ... #Toxicity #Toxicology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... tubular acidosis ... Conn's, Liddle's), Drugs ... #differential #diagnosis ... #nephrology