40 results
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... island • Osteomyelitis ... blade of grass sign ... island • Stress ... #Differential #Diagnosis
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... blade of grass sign ... ) • Enostosis/bone ... island • Stress ... #Tumors #Diagnosis
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... #Osteoporosis #pathophysiology ... #signs #symptoms ... #diagnosis
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
in subchondral bone ... architecture -> Palpable bony ... contact between bony ... Osteoarthritis #OA #pathophysiology ... #diagnosis #signs
Hyperparathyroidism - Primary vs Secondary vs Tertiary 
Lab Comparison:
 • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Symptoms: Commonly no signs ... , Fragile bones/ ... easily/weakness, Bone ... Hyperparathyroidism #diagnosis ... Secondary #Tertiary #pathophysiology
Spondylolysis & Spondylolisthesis: Pathogenesis and Clinical Findings

Pars interarticularis stress fracture (spondylolysis) - most frequently in the
tenderness • Positive one-legged ... XR — scotty dog sign ... Spondylolisthesis #MSK #diagnosis ... #pathophysiology ... #signs #symptoms
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... in macrophages Diagnosis ... Osteonecrosis, bone ... Gauchers #Disease #Diagnosis ... #Signs #Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Tuberculosis - Diagnosis ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... of bacilli to bone
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in one ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms