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hematology aplastic chronic cll leukemia lymphocytic mgus treatment workup arteritis classification differential gammopathies gammopathy gca giantcell hemeonc hodgkins lymphoma mds
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
40 ml/min A - Anemia ... marrow plasma cell ... • CML, B and T cell ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
and Management ... Summary Clinical Signs ... marrow plasma cells ... plasma clonal cell ... #Management #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... = funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Diagnosis: • ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... 5) Symptoms of anemia ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... Consider stem cell ... #diagnosis #management ... #treatment #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... marrow plasma cells ... insufficiency, Anemia ... #Significance #hematology ... #diagnosis #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... #oncology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Lymphoma (HCV) • CLL ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #oncology #management
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