11 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Vasculitis: • ... Microscopic polyangiitis ... Renal-limited vasculitis ... antibodies #diagnosis #rheumatology ... #diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
): • Microscopic ... tract, and often causes ... purpura: strong sign ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... dipstick, urine microscopy ... clinical context and signs ... Glomerulonephritis / Vasculits ... : ANCA, ANA, Anti-GBM
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... Von Willebrand disease ... - APLS • Acute ... Cryoglobulinemia (MIXED) • ANCA ... #rheumatology #
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Immune mediated injury ... basement membrane disease ... hematuria • Signs ... Diagnostic of GN or vasculitis ... of glomerular disease
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
atherosclerotic disease ... purpura: Strong sign ... )): Microscopic ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... - Urinalysis/microscopy ... - Pre-renal disease ... Glomerulonephritis or vasculitis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... - GPA, EGPA, microscopic ... classification #rheumatology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... vasculitis (AAV ... life-threatening diseases ... quantify renal injury ... Goodpasture's cause
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... kidney injury). ... renal bruit or signs ... Coarctation of aorta, Vasculitis ... Renal parenchymal disease