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differential causes nephrology management medications algorithm high hypomagnesemia reversible rhabdomyolysis treatment acidosis aniongap chronic dementia disorders druginduced encephalopathy fatigue hypokalemia
Hyperkalemia: Diagnostic algorithm Decreased renal potassium excretion • Acute renal failure • Chronic renal failure • Drugs Increased
Hyperkalemia: Diagnostic ... renal failure • Drugs ... uropathies • Drugs ... hyperplasia • Drugs ... #nephrology #potassium
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
Drugs associated ... Antimicrobials Drug-induced ... panitumumab) #Drugs ... #differential #diagnosis ... #hypomg
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Hyperkalemia ... #differential #diagnosis ... pathophysiology #pharmacology ... #potassium #medications
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Drugs II. ... Drug-induced hyperkalemia ... Potassium-sparing ... anti-inflammatory drugs ... #differential #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Endocrine • Hypo ... Liver Failure • Hypercalcemia ... Anti-Depressants • Drug ... Alcohol) • Drug ... Malnutrition / Drug
Reversible Neurocognitive Disorders (Reversible Causes of "Dementia") • Structural/Mass: Subdural Hematoma, NPH, Intracranial tumor • Infection:
• Endocrine: Hypo ... insufficiency, Hypercalcemia ... Depression, Epilepsy, Drugs ... #differential #diagnosis ... #causes #neurology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... #causes #potassium ... #high #nephrology
Causes of Hypomagnesemia Redistribution: - IV glucose - Correction of diabetic ketoacidosis - IV hyperalimentation - Refeeding
osmotic diuresis - Potassium ... renal disease Drugs ... #medications #drugs ... #pharmacology # ... hypomg
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... reactions Common Drugs ... • Recent IV potassium ... #causes #potassium ... #high #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... - Toxins - Drugs ... - Endocrine: Hypo ... Monitor potassium ... #Differential #Diagnosis
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