12 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Decreased ENaC channel ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... Heparin) • Sodium-channel ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
Drugs affecting ... to the sodium-channel ... repolarizing eflux of potassium ... #Pathophys #Pharmacology ... Antiarrhythmics #Classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS ... 1 - Sodium Channel ... 3 - Potassium Channel ... Vaughan #Williams #Pharmacology ... #pathophysiology
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
RAAS inhibiting drug ... classes (Aliskiren ... avoid harmful hyperkalemia ... RAAS inhibiting drugs ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Classification: CLASS ... 3 - Potassium Channel ... Antiarrhythmics #Pharmacology ... #pathophysiology
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
Class III Antiarrhythmics ... - Potassium Channel ... a-flutter (when other drugs ... #Channel #Blockers ... #pharmacology #
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... - Hyperkalemia ( ... , in states of hypokalemia ... #Pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Drugs (Statins), ... Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... epithelial sodium channel ... epithelial sodium channel ... Drug-associated: ... Diagnosis #High #Potassium