7 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Drugs that Impair ... Renal Potassium ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Antiarrhythmic Drugs ... Adenosine, Magnesium, Potassium ... Medications #Classes #Classification ... #Pharmacology #
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
bladder sensation, impaired ... sphincter tone: • Opiates ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology #
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
- Overview and Pathophysiology ... Utilization (VO2) • Drugs ... /Toxins • Impaired ... differential #diagnosis #pathophysiology ... #classification
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... Vaughan #Williams #Pharmacology ... #Classification ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... #Classification ... #Classes #pathophysiology