34 results
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Bimodal Age ... Most common, Wide age ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Lymphadenopathy - Differential ... • Young age ... History of Bleeding, Infection ... Asymptomatic, Age ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Increases with age ... involvement Differential ... Lymphomas • Other hematologic ... oncology #diagnosis #differential ... #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Pathophysiology: ... integrity (trauma, infection ... 1) If lesions are ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mycoplasma pneumoniae infection ... lactam antibiotics are ... spherocytosis) • Infections ... Extravascular #Causes #differential ... #diagnosis #hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
Basophilia - Differential ... granules which are ... : • helminth infections ... #Basophilia #Differential ... Diagnosis #causes #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... - Autoimmune Rheumatologic ... #Joint #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
(common causes are ... drug reaction, infection ... Strongyloides infection ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
about bacterial infections ... was placed >30d ago ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Band neutrophils are ... Neutrophil (Normal) Differential ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology ... #pathophysiology