1505 results
Brugada syndrome with non-sustained VT; sodium channel blocking drugs (e.g. amio, procainamide) can be dangerous here!

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Brugada syndrome ... non-sustained VT; sodium ... amalmattu #Brugada #syndrome
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
transporter Bartter syndrome ... limb Gitelman syndrome ... tubule Liddle syndrome ... cell epithelial sodium ... of epithelial sodium
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Increased renal sodium ... • Nephrotic Syndrome ... • Nephrotic syndrome ... Respiratory Distress Syndrome
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... hypertrophy • Sodium ... #cardiorenal #syndrome
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... dr_missyhanna #Gitelman #Syndrome
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Hypervolemic: Conn syndrome ... , Cushing syndrome ... Algorithm #nephrology #sodium
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Cirrhosis, Nephrotic syndrome ... Algorithm #diagnosis #sodium
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Cirrhosis, Nephrotic syndrome ... algorithm #diagnosis #sodium
Causes of Palpitations
 • ARRHYTHMiA 
 • SINUS ARRYTHMIA 
 • ATRIAL FIBRILLATION 
 • ATRIAL
PARKINSON WHITE SYNDROME ... SEROTONINERGIC DRUGS • SODIUM
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Repeat the sodium ... • nephrotic syndrome