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diagnosis rheumatology differential management erythematosus lupus neurology sle systemic candida candidemia cell cerebritis cryoglobulinemia cryoglobulins demyelinating disease diseases fever fungemia
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Encephalopathy, Cognitive Dysfunction ... autoantibodies that will cause ... inflammation, leading ... #neurology #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • They can cause ... Cryoglobulins Cause ... #classification ... #rheumatology #
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... multifactorial mechanisms Hematologic ... #Differential #Causes
Von Willebrand Disease Classification Type 1 (Accounts for ~3/4 of cases): • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... for ~3/4 of cases ... Qualitative defect (i.e. dysfunctional ... VonWillebrand #Disease #Classification ... #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Differential Diagnosis Algorithm ... jirovecii • CNS ... or Neutrophil Dysfunction ... #Causes #Hematology
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... Thyroid (Riedel's), CNS ... complement • Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Malignancy (e.g. hematologic ... Kikuchi disease • Type-I ... and CNS • Headache ... mild cognitive dysfunction
Invasive Fungal Infection (IFI) Invasive fungal infections are severe infections in which fungal pathogens invade normally sterile
with neutropenia, hematologic ... (most frequent cause ... species (commonly CNS ... stay and broad-spectrum ... include fever, organ dysfunction
DEMYELINATING DISEASES OF THE CENTRAL NERVOUS SYSTEM What Are Demyelinating Diseases? • Conditions that damage myelin, the protective
nervous system (CNS ... Neuromyelitis Optica Spectrum ... • Clinical Types ... bladder/bowel dysfunction ... diseases #neurology #CNS
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
Langerhans cells, a type ... various tissues, leading ... populations) CLINICAL SPECTRUM ... • Endocrine Dysfunction ... CNS involvement:
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