16 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... pathology (low level ... #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... Values and Interpretation ... Function #Tests #LFTs ... Laboratory #Values #Interpretation ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- Interpretation ... of LFTs R-value ... Hepatocellular Level ... #chemistry #diagnosis ... transaminitis #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Transaminase Levels ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... • Increased levels ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis ... #LFTs
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
sought to support a diagnosis ... Areas of diagnostic ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #Diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... disease • Liver ... conditions Diagnosis ... hypogammaglobulinemia #immunology #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
profile, including liver ... function tests (LFTs ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
UGT1A1 activity level ... of hemolysis or liver ... as jaundice on clinical ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... Ferritin levels ... disease and ILD • Liver ... Liver biopsies show ... #dermatology #diagnosis