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C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook

Clinical Presentation + Progression:
Pathophysiology: Spore ... ingestion → colonic ... immunocompromised, IBD ... 10 mg/kg IV x 1 ... infectiousdiseases #IDSA #gastroenterology
Upper and Lower Causes of GI Bleed
Upper:
 • Esophagus: Tear (Mallory Weiss, Boerhaave syndrome), Variceal, Esophagitis,
Causes of GI Bleed ... Infectious colitis, UC/Chrons ... (IBD), Radiation ... #differential #diagnosis ... #Causes #algorithm
Forrest Classification of Upper GI Bleeding
Acute Hemorrhage
  Ia - Active Spurting, Re-bleeding Risk 60-100%
Forrest Classification ... Risk 60-100% Ib ... 30% IIc - Flat Spot ... #UGIB #diagnosis ... #endoscopy #gastroenterology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Diagnosis Framework ... Family history of IBD ... Consider tumor • Upper ... Diverticulitis • IBD ... #Diagnosis #gastroenterology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Differential Diagnosis ... Algorithm Normal ... Celiac, IBD) • ... Chronic UTI) • ... #causes #pediatrics
Causes of Fat Malabsorption - Differential Diagnosis
Biliary Duct Obstruction
 • Autoimmune— PBC, PSC
 • Infection— liver
- Acquired • Chronic ... Celiac disease • IBD ... - CD, UC Altered ... length • Short ... #Causes
Montreal Classification of Crohn's Disease
Age at diagnosis (A1-A3):
   A1: < 16 yo
Montreal Classification ... : ileal L2: colonic ... ileocolonic L4: upper ... Crohns #Disease #ibd ... #diagnosis #gastroenterology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Ab • Anti-Jo-1 ... • ANA < 20 % IBM ... enzymes • Anti-Jo-1 ... pneumonia (esophagus upper ... statins - probably caused