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syndrome treatment workup classification dermatology oncology product reactions activation adultonset agglutinin algorithm anemia antimda5 antimda5dm arthritis behcet behcets cancer causes
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... • Ocular: uveitis ... #diagnosis #management ... #treatment #rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome - Diagnosis ... Diagnostic Criteria ... Abnormal pathergy test ... Most Common Clinical ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... ulceration • Ocular ... Behcet syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Polyarthritis: • Blood ... : • Complete blood ... ANA and RF (if clinical ... #testing #Rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... sensitize red blood ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
which can plug blood ... pulmonary emboli, and ocular ... : • + Clinical ... #rheumatology # ... hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... pulses, bruis, or blood ... Large Vessel: Blood ... retinopathy Lab Tests ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology
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