11 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Used Phosphate Binders ... Lower risk of hypercalcemia ... #Phosphate #Binders ... #Table #Comparison ... #Pharmacology #
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Treatment of underlying ... fluid/Lactated ringers ... per day until stable ... Diagnosis #Management #causes
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... shift • Saline Causes ... • Saline May Cause ... #pharmacology #
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Blood Pressure, Pulmonary ... Resistance, Main Uses ... #Pharmacology # ... Effect #Management #Comparison
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... hematology #diagnosis #comparison ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... & Dry) is the treatment ... the determined cause ... #table #foamed ... icu #clinical #pharmacology