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diagnosis management oncology abscess aflp apml bone classification differentiation disease fatty hemophagocytic hepatology hlh hodgkins joint liver lung lymphohistiocytosis lymphoma
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... dx and stage ... Osteomyelitis / Septic ... • Differentiate ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Pleuritic chest pain ... Blood cultures • CXR ... early disease) • CXR ... shows a small, stable
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++ (Plt, Hb), Hepatic ... ↑ sIL-2R >2400 Ul ... Treatment: • ... #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... common • Imaging: CXR ... initiation • Differential ... diagnosis #management #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... vomiting, abdominal pain ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Management Summary Causes ... - Abdominal pain ... ) • AKI: BUN/Cr ... per day until stable
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... • Early Stage ... classification #hematology
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