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diagnosis management table differential hematology lupus treatment agraphia ana antibody antinuclear cerebritis clinical cns crisis cytoplasmic disorders druginduced endocarditis erythematosus
Alexia Without Agraphia Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
Alexia without ... the most common cause ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... test, ANA (e.g., SLE ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Workup #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 10% of all lupus cases ... Discontinuation of causal ... #comparison #table ... #rheumatology #
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Scl70 (in some cases ... Scl-70 (in some cases ... body-like: - Neurologic ... OSs, cerebellar ataxia ... differential #diagnosis #rheumatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... transfusion • Pathophysiology ... #diagnosis #comparison ... #table
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... ↑ sIL-2R >2400 Ul ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... treatment #summary #rheumatology
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
conditions: Autoimmune (SLE ... Blood cultures/serology ... in up to 30% of cases ... #Endocarditis #comparison ... Marantic #diagnosis #table
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
microangiopathic hemolytic anemia ... (MAHA) Pathophysiology ... • Refractory cases ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
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