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management differential druginduced lupus nephrology table acidosis anemia aplastic capsulatum classification comparison diuresis diuretics drugs elevation erythematosus excretion hematology hemophagocytic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... life-threatening • Treatment ... #comparison #table ... #rheumatology # ... diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
↑ sIL-2R >2400 Ul ... Autoimmune diseases: SLE ... Treatment: • ... #management #treatment ... #summary #rheumatology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... only if no clear cause ... and Elimination (see ... Table below) ... STOP offending medications
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... - HIV/HAART medications
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... aplastic anemia Treatment ... years who have a suitable ... #diagnosis #management
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
disequilibrium syndrome • Diagnosis ... Kidney stones caused ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology ... #Medications #Table
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
for 1 year of treatment ... Erythematosus #medications ... #drugs #pharmacology ... #differential #diagnosis ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
IDSA Recommendations for Preventing and Treating Histoplasma Capsulatum Infections in HIV-AIDS Indications for Initiating Primary Prophylaxis: •
histoplasmosis (>10 cases ... interactions with ARV (see ... Table 5) and itraconazole ... IDSA #Prevention #Treatment ... infections #HIVAIDS #pharmacology
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