11 results
Myxedema coma and thyroid storm are thyroid emergencies associated with increased mortality. Prompt recognition of these
coma and thyroid storm ... extremely reduced or elevated ... Management of myxedema ... coma and thyroid storm ... , #hyperthyroidism
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
High Output Heart ... Failure - Pathophysiology ... Disease - Especially COPD ... Hematopoiesis Hyperthyroidism ... cardionerds #High
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... ) • High CO2 = ... High ICP: 20. ... Hemorrhage #ICH #elevated
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... Lysis Syndrome: • Pathophysiology ... Spontaneous if high ... TLS #diagnosis #management
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Hyperdynamic circulation/High ... heart failure: - Hyperthyroidism ... overdrive • Elevated ... Differential #Diagnosis #Pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
fractures of feet, thigh ... nephrocalcinosis • CPPD ... Wilson's disease • hypothyroidism ... collection with EDTA Pathophysiology ... intracranial pressure - Elevated
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... ) Pathophysiology ... calcium to form CPP ... Hyperparathyroidism • Hypothyroidism ... Rheumatology #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... • Attempt if high ... if WBC > 5 or elevated ... APML #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Person Syndrome Pathophysiology ... , diaphoresis, high ... Diagnosis: • High ... with SPS have elevated
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Lymphohistiocytosis (HLH) High ... - Persistent high ... Pathophysiology ... • Cytokine storm ... Elevated soluble