9 results
Pharmaceutical Management of Hyperthyroidism / Thyroid Storm
Beta-Blockers 
• Decreases sympathetic hyperactivity 
• Partially blocks peripheral conversion
Management of Hyperthyroidism ... / Thyroid Storm ... after synthetic pathway ... may accompany storm ... #Hyperthyroidism
Thyroid Function Pathway 

Hypothyroidism is a very common condition! Here's a repost of the pathway that
Thyroid Function ... Pathway Hypothyroidism ... HIGH TSH and a low ... because if T4 is low ... #Pathway #Pathophysiology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism ... Manifestation of Hyperthyroidism ... Diagnosis: • ↓ Low ... ↑ Free T4 • Thyroid ... Storm: • Life
Thyrotoxic Periodic Paralysis - Illness Script
 • Epidemiology: Asian men age 20-30 with hyperthyroidism of any
age 20-30 with hyperthyroidism ... and menses • Pathophysiology ... pump by excess thyroid ... Hypokalemia +/- low ... triggers, Treat hyperthyroidism
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
CPPD vs Gout ... About CPPD When ... disease states Pathophysiology ... activate inflammatory pathways ... Hyperparathyroidism • Hypothyroidism
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low ... nephrocalcinosis • CPPD ... Wilson's disease • hypothyroidism ... collection with EDTA Pathophysiology
Pathogenesis of Select Causes of Constipation in Adults and in Elderly

 • Mechanical (ex. Bowel Obstruction,
-> Interrupted flow ... Hypothyroidism) ... -> Thyroid hormone ... unknown, many pathways ... #constipation #pathophysiology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Deposition Disease (CPPD ... ) Pathophysiology ... calcium to form CPP ... activate inflammatory pathways ... Hyperparathyroidism • Hypothyroidism
Hypophosphatemia and Hypoxia - Pathophysiology

↓ Phosphate leads to ↓ red cell 2,3-DPG and a  reduction
and Hypoxia - Pathophysiology ... Rapoport-Leubering pathway ... weakness (defined as low ... inspiratory pressure or low ... respiratory #hypoxia #pathophysiology