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diagnosis hematology management clinical physicalexam differential msk orthopedics syndrome tenosynovitis wrist deficiency dequervains oncology test anemia eichhoffs nutrition algorithm eosinophilia
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Treatment of Thrombotic ... HUS) Treatment ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
disorders • Shear stress-induced ... Diagnosis #Management #treatment ... #hematology #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
folate that can cause ... mobilize folate stores ... depleted tissue stores ... differential #diagnosis #hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
validated for VTE treatment ... Bleeding #Risk #Scores ... Anticoagulation #Factors #Hematology
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
with low B12 stores ... normal tissue stores ... tissue folate stores ... Diagnosis #Nutrition #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
total body iron stores ... Fe #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... Differential #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... of (Acute resp distress ... : No • Treatment ... Transfusion #Reactions #hematology
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