20 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... #APML #diagnosis ... #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... Criteria: • Elevated ... transformation into AML ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
- Caine Criteria ... Anorexia nervosa Treatment ... can improve symptoms ... development of Korsakoff syndrome ... #Management #neurology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... of (Acute resp distress ... : No • Treatment ... #diagnosis #comparison
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... vancomycin (if SSTI or port ... : - Seen with AML ... (~20 %) and APL ... #HemeOnc #Diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic Symptoms ... Symptoms: • The ... Criteria for Diagnosis ... disease: symptomatic treatment ... #Syndrome #dermatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... criteria for MS ... Multiple Sclerosis Treatment ... #management #neurology ... #treatment #MS
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Pinpoint-sized red spots ... factor (GCSF) treatments ... #diagnosis #hematology ... #oncology