65 results
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
four interrelated steps ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
K), H. pylori test ... thyroid function test ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... - Ice cube test ... , TempTest test ... Urticaria #diagnosis #rheumatology ... #comparison #table
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Algorithm and Causes ... #Differential #Causes ... #Workup #Hematology ... GrepMed Recommended Text
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... total body iron stores ... Fe #diagnosis #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Complement: Post-strep ... diagnosis #algorithm #rheumatology
Sensitivity is the proportion of truly diseased persons in the screened population who are identified as
they have high scores ... correctly diagnose a case ... that any given case ... implies being able ... #Calculation #Table
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... of (Acute resp distress ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... invade URT & via hematologic ... CNS and hematologic ... lymph -> Koplik's spots ... peds #pediatrics #pathophysiology