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Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Study • Clotting tests ... • Clotting tests ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Non malignant hematologic ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Treatment of Thrombotic ... HUS) Treatment ... PLEX and RTX • Short-term ... #rheumatology # ... hematology
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
four interrelated steps ... #Hemostasis #Pathophysiology ... Coagulation #Cascade #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
K), H. pylori test ... thyroid function test ... patients if the cause ... or if a primary hematologic ... #Workup #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... #Differential #Causes ... #Workup #Hematology ... GrepMed Recommended Text
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... total body iron stores ... Fe #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
without other cause ... : 33% • Treatment ... of (Acute resp distress ... : No • Treatment ... Transfusion #Reactions #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Complement: Post-strep ... diagnosis #algorithm #rheumatology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... invade URT & via hematologic ... CNS and hematologic ... lymph -> Koplik's spots ... peds #pediatrics #pathophysiology
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