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diagnosis hepatology differential liver management causes nephrology aki indications lfts transaminitis aclf aih albumin alcoholic autoimmune chemistry chronic dili druginduced
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... those with CLD (± cirrhosis ... months without treatment ... Circulation Failure Kidney ... Drug-Induced Liver Injury
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Differential Diagnosis Algorithm ... HBV, HCV, HEV, EBV ... : < 1 • Cirrhosis ... #diagnosis #algorithm
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 20x normal - Acute ... normal - Infection (EBV ... CMV), Alcoholic cirrhosis ... Patterns #Liver #Injury
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... Skin involvement, Kidney ... non-essential drug/HDS treatments ... HBV, HCV, HEV, EBV ... dechallenge • Acute
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... GN: ANCA, Anti-GBM ... SCVMCMed #AKI #Acute ... #Kidney #Injury ... nephrology #causes #algorithm
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... ascites removed • Acute ... kidney injury ( ... Indications #Management #Cirrhosis ... #treatment #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... C, A, E, B, D, EBV ... Sophia_Hayes_MD #Liver #Injury ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... Cardiac muscle, Kidneys
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... ANCA, ANA, Anti-GBM ... cryoglobulins, hepatitis ... #Kidney #Injury
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... with severe liver injury ... > 3 mg/dL) or acute
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