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Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Differential Diagnosis ... , Compartment syndrome ... , Electrical injury ... Monitor potassium ... Dialysis for severe hyperkalemia
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - ... Differential Diagnosis ... Monitor potassium ... #Differential #Diagnosis ... causes #treatment #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... K+: • Tissue injury ... Hemolysis • Rhabdomyolysis ... • Tumor lysis syndrome ... blockers - MCW Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... • Trauma/Crush injury ... - Tumor lysis syndrome ... - Rhabdomyolysis ... #high #nephrology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... Cancer Related ... • Hypercalcemia ... #Differential #Diagnosis ... Classification #Nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... • Trauma/Crush injury ... - Tumor lysis syndrome ... - Rhabdomyolysis ... #high #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... , rhabdo/crush injury ... reabsorption) Workup ... #Treatment #potassium ... #nephrology #K
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
• Unexplained hypokalemia ... (renal potassium ... • Seizures • Rhabdomyolysis ... Supplement: • Potassium ... #diagnosis #nephrology
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
neuromuscular injury ... malignancy, metastatic cancer ... antiphospholipid syndrome ... #Differential #Diagnosis ... #High #Potassium